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. 2018 Oct 10;9(21):3950–3961. doi: 10.7150/jca.25967

Figure 7.

Figure 7

Expression of CDK5 in human cancer cell lines (A) and CDK5 promoted the proliferation ability of lung cancer cells in vitro (B-D). (A) The expression of CDK5 was detected in six cancer cell lines and two normal cell lines by western blot. β-actin was used as internal control. (B) Proliferation assay of MTT experiments was performed in A549 cells transfected with NC siRNA or CDK5 siRNA, NC: Normal control. Error bars represent the mean ± s.d. of three independent experiments. (C) The growth inhibitory rate of A549 after treated with roscovitine at the concentration for 10um, 20um, 40um. Error bars represent the mean ± s.d. of three independent experiments. (D) Colony-formation assays was used for detecting the proliferation ability in A549 cell line after treated with roscovitine. (# p<0.05; * p<0.01; ** p<0.001).