Figure 1.

Clinical Features of Individuals with NFIB Haploinsufficiency

Craniofacial phenotype of individuals P1, P4, P9, P10a, P10b, P11, P13, P14, and P15. The pictures show individual P9 at the age of 11 months and at the age of 4. Individual P13 is represented at the ages of 7 and 10 years, while P15 is represented at the ages of 9 and 17 years. Note the long face with the high forehead, sparse eyebrows, down-slanting palpebral fissures and mild blepharophimosis, a narrow nasal bridge, anteverted nares, and a long and smooth philtrum.