Skip to main content
. 2018 Sep 19;13(10):1542–1549. doi: 10.2215/CJN.01770218

Figure 2.

Figure 2.

Calcium excretion during the sodium chloride (NaCl) infusion test in 370 patients according to claudin-14 rs219755 (A>G) genotype. Patients carrying the A allele had lower calcium excretion in response to NaCl infusion compared with patients with the GG genotype. Analysis was conducted with ANOVA for repeated measures (P<0.01). The analysis was also significant when adjusted for age, sex, body mass index, and urinary sodium excretion at the end of infusion (P<0.01). Pairwise comparisons: P=0.003, AA versus GA; P<0.001, AA versus GG. Calcium excretion was expressed as micrograms per minute in 24-hour urine and three urine samples collected during the NaCl infusion test (equilibration, NaCl infusion, and recovery). Sample size: AA, n=20; GA, n=148; GG, n=202.