Table 12.
Stability studies of S2 ISG formula compared to free AZM in gel.
Parameters | Formulation code | Sampling time |
||||
---|---|---|---|---|---|---|
Initial | 1 week | 2 weeks | 4 weeks | 8 weeks | ||
Drug content (%) | S2 ISG | 99.8 | 98.70 | 97.60 | 97.18 | 80.99 |
Free drug in gel | 100 | 97.80 | 87.30 | 80.23 | 76.23 | |
pH measurement | S2 ISG | 7.01 ± 0.03 | 7.20 | 7.12 | 6.91 | 6.92 |
Free drug in gel | 6.86 ± 0.2 | 6.78 | 6.94 | 6.93 | 7.20 |