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DKK3 associates with higher tubulointerstitial fibrosis. (A) Tubulointerstitial fibrosis in patients who underwent diagnostic kidney biopsies according to urinary Dickkopf-3 (DKK3)-to-creatinine concentrations. (B) Representative kidney biopsy specimens from three patients with membranous nephropathy (upper panels) and three patients with focal segmental sclerosis (lower panels) according to urinary DKK3-to-creatinine concentrations.
