Table 1.
Participant’s baseline characteristics of the subcohort (n = 694).a
| Baseline plasma tryptophan |
|||||
|---|---|---|---|---|---|
| Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | P valueb | |
| N | 167 | 172 | 174 | 181 | |
| Age, years | 67.5 ± 5.4 | 66.8 ± 6.1 | 66.2 ± 5.6 | 65.6 ± 5.6 | 0.01 |
| Sex, % women | 80.2 | 65.7 | 58.6 | 48.1 | <0.01 |
| Intervention group, % | |||||
| MedDiet + EVOO | 34.1 | 30.8 | 28.7 | 29.3 | 0.08 |
| MedDiet + nuts | 31.7 | 36.1 | 38.5 | 42.0 | |
| Control | 34.1 | 33.1 | 32.8 | 28.7 | |
| Hypertension, % | 86.8 | 93.6 | 91.4 | 91.2 | 0.29 |
| Dyslipidemia, % | 88.0 | 90.7 | 83.3 | 78.5 | <0.01 |
| Smoking, % | |||||
| Never | 70.7 | 59.3 | 55.8 | 58.6 | 0.02 |
| Former | 16.2 | 26.2 | 20.7 | 27.1 | |
| Current | 13.2 | 14.5 | 23.6 | 14.4 | |
| Waist circumference, cm | 99.2 ± 10.5 | 98.9 ± 9.9 | 99.3 ± 11.4 | 100.8 ± 11.0 | 0.35 |
| Leisure-time physical activity (MET), min/d | 198 ± 189 | 250 ± 21 | 263 ± 275 | 240 ± 242 | 0.06 |
| Body mass index, kg/m2 | 30.0 ± 3.6 | 30.0 ± 3.4 | 29.7 ± 3.5 | 30.1 ± 3.8 | 0.61 |
| Total energy intake, kcal/d | 2249 ± 522 | 2270 ± 586 | 2273 ± 540 | 2314 ± 608 | 0.74 |
| MedDietscore (0 to 14 score)c | 8.6 ± 2.0 | 8.5 ± 1.9 | 8.6 ± 2.1 | 8.7 ± 1.9 | 0.68 |
| Baseline glucose, mg/dl | 101.7 ± 15.4 | 100.8 ± 16.0 | 99.1 ± 14.5 | 97.6 ± 15.8 | 0.07 |
a
Continuous variables ± standard deviation.
b
Mantel-Haenszel chi-squared P value for categorical variables and ANOVA P values for continuous variables.
c
MedDiet score was calculated by responses on a 14-item questionnaire. Higher score signifies greater adherence to a Mediterranean diet pattern.