Table 4:
Mitral Regurgitation and MVP: Relationship to 3D Mitral Valve Parameters.
| MR ≥ Moderate n=5 |
MR ≤ Mild n=49 |
p | MVP n=19 |
No MVP n=35 |
p | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Marfan Syndrome (n, %) | 5 | (100%) | 22 | (45%) | - | 19 | (100%) | 8 | (35%) | - |
| Annular Parameter | ||||||||||
| AP-Diameter (cm/M) | 4.1 | (4.0–4.2) | 2.7 | (2.4–2.9) | 0.007 | 3.1 | (2.5–3.5) | 5.8 | (4.3–5.8) | 0.003 |
| AL-PM diameter (cm/M) | 4.3 | (4.1–4.5) | 2.9 | (2.6–3.2) | 0.003 | 3.5 | (2.8–4.3) | 2.9 | (2.6–3.1) | <0.001 |
| Annular width at commissure (cm/M) |
4.1 | (4.0–4.2) | 2.9 | (2.6–3.2) | 0.003 | 3.4 | (2.7–4.1) | 2.9 | (2.6–3.0) | <0.001 |
| Sphericity | 0.86 | (0.85–0.90) | 0.92 | (0.89–0.98) | 0.14 | 0.90 | (0.85–0.93) | 0.92 | (0.89–0.97) | 0.22 |
| Annulus circumference (cm/M2) | 12 | (12.4–13.2) | 9.6 | (8.5–10.1) | 0.006 | 10.7 | (8.9–12.7) | 9.3 | (8.3–9.9) | 0.002 |
| Annulus area (cm2/M2) | 11.9 | (11.0–13.3) | 6.8 | (5.5–7.5) | 0.008 | 8.6 | (5.9–11.9) | 6.5 | (5.1–7.2) | <0.001 |
| Annulus height (cm/M) | 0.62 | (0.46–0.68) | 0.66 | (0.53–0.77) | 0.49 | 0.6 | (0.5–0.7) | 0.7 | (0.6–0.8) | 0.14 |
| AHCWR | 0.15 | (0.14–0.15) | 0.23 | (0.20–0.26) | 0.01 | 0.16 | (0.14–0.22) | 0.24 | (0.21–0.27) | <0.001 |
| Non-Planar Angle (°) | 151 | (149–167) | 141 | (134–150) | 0.02 | 150 | (144–162) | 137 | (132–146) | <0.001 |
| Leaflet Parameter | ||||||||||
| Total Leaflet Area (cm2/ M2) | 13.1 | (12.0–15.9) | 7.7 | (6.4–8.4) | 0.009 | 9.1 | (6.4–13.1) | 7.7 | (6.3–8.1) | 0.006 |
| Anterior Leaflet Area (cm2/M2) | 6.9 | (5.8–7.7) | 4.3 | (3.7–4.8) | 0.004 | 4.8 | (4.1–10.9) | 6.5 | (5.1–7.2) | 0.021 |
| Posterior Leaflet Area (cm2/M2) | 7.3 | (5.2–8.1) | 3.3 | (2.4–3.7) | 0.008 | 4.1 | (2.9–7.3) | 3.2 | (2.4–3.5) | 0.018 |
| Anterior Leaflet Length (cm/M) | 2.2 | (2.1–2.4) | 2.1 | (1.8–2.2) | 0.09 | 2.1 | (1.8–2.2) | 2.2 | (1.9–2.2) | 0.94 |
| Posterior Leaflet Length (cm/M) | 1.6 | (1.3–1.8) | 1.0 | (0.9–1.2) | 0.02 | 1.2 | (1.0–1.6) | 1.0 | (0.9–1.1) | 0.026 |
| Tenting Height (mm/M) | 1.6 | (1.6–3.2) | 5.8 | (4.1–6.8) | 0.004 | 2.8 | (1.6–4.9) | 6.3 | (5.4–7.0) | <0.001 |
| Tenting Area (cm2/M2) | 0.58 | (0.12–0.74) | 0.91 | (0.58–1.12) | 0.19 | 0.5 | (0.1–0.8) | 1.0 | (0.7–1.2) | <0.001 |
| Billow Volume (cc/M2) | 1.07 | (0.61–3.3) | 0.02 | (0.01–0.05) | <0.001 | 0.13 | (0.04–0.73) | 0.01 | (0.01–0.03) | <0.001 |
| Tenting Volume (cc/M2) | 0.32 | (0.12–0.94) | 0.96 | (0.67–1.57) | 0.05 | 0.51 | (0.13–0.96) | 1.22 | (0.82–1.61) | <0.001 |
Values are listed as median (IQR), P-values calculated by Wilcoxon rank sum test.
A-P: Anterior-Posterior, AL-PM: Anterolateral-Posteromedial
AHCWR: Annular height to commissural width ratio, BSA: Body Surface Area