Table 3.

Association of LIPC SNPs with visceral adiposity indicators, TyG index related parameters and insulin resistance

SNPs	Genotypes			P* (adjusted P)	P** (adjusted P)
	MM	Mm	mm
rs2043085	CC	CT	TT
LAP	2863.0 ± 2180.5	3609.6 ± 3537.8	4451.0 ± 5943.0	1.8 × 10−7 (3.2 × 10−6)	0.016 (0.288)
VAI	183.8 ± 132.6	219.0 ± 203.6	266.4 ± 381.5	2.4 × 10−7 (4.3 × 10−6)	0.011 (0.198)
TyG	8.5 ± 0.6	8.6 ± 0.7	8.8 ± 0.7	1.7 × 10−5 (3.1 × 10−4)	0.542
TyG-BMI	202.5 ± 35.0	211.7 ± 39.7	217.9 ± 38.1	2.0 × 10−5 (3.6 × 10−4)	0.026 (0.468)
TyG-WC	713.2 ± 109.5	736.9 ± 118.3	765.7 ± 117.6	1.4 × 10−6 (2.5 × 10−5)	0.013 (0.234)
HOMA-IR	2.2 ± 1.3	2.2 ± 1.4	2.3 ± 1.5	0.422	0.818
rs1532085	GG	GA	AA
LAP	2876.5 ± 2181.0	3613.7 ± 3519.0	4470.7 ± 6085.4	4.5 × 10−7 (8.1 × 10−6)	0.040 (0.720)
VAI	184.1 ± 132.1	218.5 ± 202.5	270.1 ± 390.5	2.9 × 10−7 (5.2 × 10−6)	0.029 (0.522)
TyG	8.5 ± 0.6	8.6 ± 0.7	8.8 ± 0.7	1.0 × 10−5 (1.8 × 10−4)	0.701
TyG-BMI	202.8 ± 35.1	211.9 ± 39.5	217.3 ± 38.8	5.1 × 10−5 (9.2 × 10−4)	0.051 (0.918)
TyG-WC	713.4 ± 110.4	738.4 ± 117.3	763.2 ± 119.7	4.7 × 10−6 (8.5 × 10−5)	0.034 (0.612)
HOMA-IR	2.2 ± 1.3	2.2 ± 1.4	2.3 ± 1.5	0.449	0.766
rs1800588	CC	CT	TT
LAP	3385.6 ± 3198.8	3746.4 ± 4593.1	3514.7 ± 3246.5	0.026 (0.468)	0.288
VAI	208.8 ± 184.7	230.6 ± 290.1	207.7 ± 176.1	0.003 (0.054)	0.163
TyG	8.6 ± 0.6	8.6 ± 0.7	8.8 ± 0.7	4.6 × 10−4 (0.008)	0.521
TyG-BMI	210.2 ± 37.4	211.9 ± 39.0	205.6 ± 39.2	0.455	0.242
TyG-WC	735.2 ± 116.2	739.7 ± 115.5	726.4 ± 125.0	0.182	0.303
HOMA-IR	2.2 ± 1.4	2.2 ± 1.4	2.2 ± 1.5	0.219	0.632

Abbreviations as in Table 1

MM homozygosity of major allele, Mm heterozygosity, mm homozygosity of minor allele

Adjusted P: the P value were shown with Bonferroni corrections, n = 18

P*: adjusted for age, sex, current smoke, hypertension medicine, HDL-C; P**: Further adjusted for TG