Table 3.

12-month, seasonal and monthly adherence

	n	mean ± sd	median	min-max
12 month adherence to Rebif® - Rebismart® (Per Protocol Set)	46	98.32 ± 2.628	99.09	90.30–100
Study adherence to Rebif® - Rebismart® (Full Analysis Set)	62	97.93 ± 5.704	100	90.30–100
Seasonal adherence
Jan-Mar	61	98.02 ± 6.879	100	57.97–100
Apr-Jun	57	98.36 ± 5.678	100	60.94–100
Jul-Sep	55	98.58 ± 3.276	100	81.63–100
Oct-Dec	56	97.91 ± 6.837	100	52.0–100
Monthly adherence
Jan	60	97.54 ± 10.409	100	33.33–100
Feb	60	97.56 ± 8.513	100	54.55–100
March	59	98.34 ± 7.192	100	54.17–100
April	57	98.60 ± 6.826	100	50.00–100
May	57	98.67 ± 6.795	100	52.00–100
June	53	98.21 ± 5.560	100	65.00–100
July	52	98.45 ± 5.777	100	60.87–100
August	49	98.873 ± 2.935	100	86.67–100
September	52	98.46 ± 4.073	100	81.25–100
October	53	99.01 ± 2.963	100	86.67–100
November	52	97.933 ± 6.282	100	68.42–100
December	59	98.14 ± 6.721	100	52.00–100

Annual adherence: 100 × (total no of injections in 12 months) / expected no of infections in the respective months

Seasonal adherence: 100 × (total no of injections in a 3 month-period) / expected no of infections during the same period

Monthly adherence: 100 × (total no of injections in specific month) / expected no of infections