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. 2018 Nov 6;18:1066. doi: 10.1186/s12885-018-4963-8

Table 5.

Scoring model for the prediction of non-AIDS-defining cancers (NADCs) in HIV-infected patients (N = 1001)

Score No. of NADCs/ Non-NADCs Cumulative incidence rate of NADCs at 5 years (95% CI) Cumulative incidence rate of NADCs at 10 years (95% CI) Hazard ratio (95% CI)
0 2/ 222 0.9 (0.2–3.7) 0.9 (0.2–3.7) 1 (reference)
1 1/ 91 0 1.4 (0.2–9.7) 0.9 (0.08–10.2)
2 6/ 273 0.4 (0.1–2.8) 1.4 (0.4–4.4) 2.5 (0.5–12.3)
3 8/ 174 2.9 (1.2–6.9) 2.9 (1.2–6.9) 5.1 (1.1–23.9)
4 11/ 101 5.8 (2.7–12.5) 10.7 (5.5–20.4) 12.6 (2.8–56.7)
≥5 33/ 79 20.2 (13.5–29.7) 41.3 (29.7–55.3) 53.2 (12.7–222.5)
Total 61/ 940 P for trend < 0.001

C-statistics: 0.8 (95%CI, 0.8–0.9, P < 0.001)

Note. Based on the final model’s regression coefficients (Table 4), 1 point each was assigned to blood transmission, and HBV, 2 points each were assigned to age 40–49, smoker, and IDU, 3 points was assigned to age 50–59, age 60–69, and 4 points was assigned to age ≥ 70. Abbreviations: CI confidence interval, HBV hepatitis B virus, IDU injection drug use, NADCs non-AIDS-defining cancers