Table 2.
Laboratory parameters upon ICU admission and IL-6 rate of change after 24 h ICU admission (n = 123)
| Laboratory parameters | Survival (n = 48) Mean ± SD |
Non- survival (n = 75) Mean ± SD |
p (Student’s t-test) |
|---|---|---|---|
| Hemoglobin (g/dL) | 11.3 ± 2.3 | 11.0 ± 2.6 | 0.50 |
| White blood cells (K/mm3) | 20.6 ± 14.2 | 18.1 ± 13.2 | 0.34 |
| Platelets (K/mm3) | 164 ± 126 | 193 ± 134 | 0.24 |
| Blood glucose (mg/dL) | 129.3 ± 80.8 | 138.6 ± 77.8 | 0.55 |
| Blood–urea–nitrogen (mg/dL) | 35.7 ± 21.6 | 45.9 ± 25.1 | 0.02 |
| Creatinine (mg/dL) | 1.97 ± 1.5 | 2.47 ± 1.6 | 0.08 |
| Bilirubin (mg/dL) | 2.40 ± 2.4 | 3.34 ± 4.6 | 0.17 |
| Prothrombin time (s) | 16.9 ± 5.4 | 18.6 ± 10.0 | 0.27 |
| aPTT (s) | 35.9 ± 9.4 | 42.9 ± 20.8 | 0.02 |
| pH | 7.33 ± 0.1 | 7.28 ± 0.10 | 0.04 |
| PaCO2 (mmHg) | 35.6 ± 7.8 | 33.5 ± 9.3 | 0.21 |
| PaO2 (mmHg) | 120.4 ± 79.3 | 129.9 ± 99.6 | 0.58 |
| HCO−3 (mmol/L) | 19.0 ± 4.4 | 16.4 ± 5.8 | 0.01 |
| C-reactive protein (mg/L) | 123.3 ± 45.7 | 122.4 ± 60.8 | 0.93 |
| Procalcitonin (ng/dL) | 42.5 ± 109.8 | 54.4 ± 91.4 | 0.16 |
| Lactate (mmol/L) | 4.2 ± 2.6 | 5.3 ± 4.3 | 0.59 |
| IL-6 rate of change | 0.8 ± 4.5 | −0.7 ± 0.3 | 0.04 |
aPTT, activated partial thromboplastin time; PaCO2, arterial pressure of carbon dioxide; PaO2, arterial pressure of oxygen; HCO−3, bicarbonate
IL-6 rate of change = (IL-6 (T0) – IL-6 T24)/ IL-6 T0