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. 2018 Nov 6;18:39. doi: 10.1186/s12873-018-0191-4

Table 4.

Association of IL-6 reduction rate and survival for sepsis and septic shock in logistic regression analysis (n = 123)

Univariate Multivariate
OR (95%CI) OR (95%CI)
IL-6 reduction rate (quartile)
 Q1: 100% to 86% 5.08 (1.60–16.1) 5.67 (1.27–25.3)
 Q2: 85% to 50% 1.45 (0.52–4.11) 1.86 (0.44–7.94)
 Q3: 49% to 0% 0.64 (0.22–1.83) 0.54 (0.14–2.02)
 Q4: Increased ref ref

Adjusted for age, sex, BUN, Cre, aPTT, pH, HCO3

ref: Reference

OR Odds Ratio, CI Confidence Interval

IL-6 reduction rate = (IL-6 (T0) – IL-6 T24)/ IL-6 T0

T0: At admission time

T24: 24 h after ICU admission