Table 1.
The Characteristics of Selected Studies
| Author | Year | N | Country | Study design | Assays used |
TSH Cut-off |
ART details |
Outcomes |
|---|---|---|---|---|---|---|---|---|
| Coelho | 2016 | 650 | Brazil | retrospective | a third-generation assay | 2.5:4.0 | IVF/ICSI | PR; CPR; LBR; MR |
| Aghahosseini | 2013 | 816 | Iran | retrospective | NS | 2.5 | IVF | CPR |
| Mintziori | 2014 | 158 | Greece | retrospective | ELISA | 2.5 | IVF | PR; CPR; LBR; MR |
| Unuane | 2017 | 3143 | Belgium | retrospective | NS | 2.5 | IUI | PR; LBR; MR |
| Michalakis | 2011 | 1216 | USA | retrospective | NS | 2.5;4.0 | NS | PR; CPR; LBR; MR |
| Muller | 1999 | 141 | Netherlands | prospective | an immunoluminometric assay | 4.5 | IVF | PR; LBR; MR |
| Chai | 2014 | 505 | China | retrospective | Access HYPERsensitive hTSH Reagent Pack and Access Free T4 Reagent Pack |
2.5;4.5 | IVF/ ICSI |
CPR; LBR; MR |
| Baker | 2006 | 146 | USA | retrospective | chemiluminometric technology | 2.5 | IVF | LBR |
| Karmon | 2014 | 1477 | USA | prospective | third-generation assays | 2.5 | IUI | CPR; LBR |
| Weghofer | 2015 | 98 | USA | retrospective | Electrochemiluminescence immunoassay |
2.5 | IVF | CPR; LBR |
| Seungdamrong | 2017 | 1306 | USA | prospective | Immulite 2000 system | 2.5 | IUI | PR; CPR; LBR; MR |
| Wu | 2017 | 138 | China | prospective | NS | 2.5; 5 | IVF/ ICSI |
PR; CPR; LBR; MR |
| Ba | 2013 | 413 | China | prospective | NS | 4.2 | IVF/ ICSI |
PR; CPR; LBR; MR |
| Zhang | 2012 | 1832 | China | retrospective | NS | 3.9 | IVF/ ICSI |
PR; CPR; LBR; MR |
| Zeng | 2014 | 375 | China | prospective | Chemiluminescent immunoassay |
2.5;3.5 | IVF/ ICSI |
CPR; LBR; MR |
| Gingold | 2016 | 1201 | USA | retrospective | NS | 2.5;5.0 | IVF | PR; CPR; LBR |
| Reh | 2010 | 1055 | USA | retrospective | NS | 2.5;4.5 | IVF | CPR; LBR; MR |
| Cai | 2017 | 176 | China | prospective | electro- chemiluminescence immunoassays | 2.5 | IVF | CPR; LBR; MR |
IVF In vitro fertilization, ICSI intracytoplasmatic sperm injection, IUI intra-uterine insemination, ART assisted reproduction technology, TSH thyroid stimulating hormone, CPR clinical pregnancy rate, MR miscarriage rate, LBR live birth rate, PR pregnancy rate, ELISA enzyme-linked immunosorbent assay