Fig. 7.

GPNMB transfection’s effect on invasion. Invasion showed 2.2-fold decrease through matrigel-coated transwell polycarbonate membranes (8 μm pore size) compared with control transfects. The bar chart shows the mean number of cell invasiveness of four independent experiments (P = 0.01, two side Student t test). Mock: negative control, empty vector (pEF1); and GPNMB expressing HCT116 cell line