Table 2.
Multivariable Cox regression for propensity-score matched (PSM) dataset
| Variable | Cancer-Specific mortality | All-cause mortality | ||
|---|---|---|---|---|
| HR (95% CI) | p-value | HR (95% CI) | p-value | |
| Age | 1.01 (1.00, 1.02) | 0.0027 | 1.02 (1.01, 1.02) | <.0001 |
| Sex | ||||
| Male | Ref. | Ref. | ||
| Female | 0.86 (0.73, 1.02) | 0.0781 | 0.82 (0.70, 0.96) | 0.0108 |
| Race | ||||
| White | Ref. | Ref. | ||
| Black | 0.88 (0.68, 1.14) | 0.3278 | 0.88 (0.69, 1.11) | 0.2748 |
| Others | 0.96 (0.72, 1.27) | 0.7764 | 0.95 (0.73, 1.24) | 0.7033 |
| Grade | ||||
| I/ II | Ref. | Ref. | ||
| III/ IV | 1.28 (1.07, 1.52) | 0.0066 | 1.26 (1.07, 1.49) | 0.0052 |
| Unknown | 0.83 (0.61, 1.11) | 0.2023 | 0.82 (0.62, 1.08) | 0.1509 |
| Histology | ||||
| Adenocarcinoma | Ref. | Ref. | ||
| Squamous cell | 0.82 (0.67, 1.00) | 0.0503 | 0.85 (0.70, 1.03) | 0.0928 |
| Others | 0.88 (0.73, 1.06) | 0.1743 | 0.93 (0.78, 1.11) | 0.4148 |
| T classification | ||||
| T1 | Ref. | Ref. | ||
| T2 | 1.27 (1.00, 1.60) | 0.0476 | 1.26 (1.01, 1.56) | 0.0375 |
| T3 | 1.64 (1.20, 2.24) | 0.0020 | 1.49 (1.11, 2.00) | 0.0082 |
| T4 | 1.34 (1.01, 1.78) | 0.0444 | 1.24 (0.95, 1.63) | 0.1121 |
| N classification | ||||
| N0/N1 | Ref. | Ref. | ||
| N2/N3 | 1.50 (1.17, 1.92) | 0.0014 | 1.38 (1.09, 1.74) | 0.0065 |
| Extent of Surgery | ||||
| Lobectomy or Bilobectomy | Ref. | Ref. | ||
| Pneumectomy | 1.16 (0.94, 1.43) | 0.1593 | 1.15 (0.95, 1.40) | 0.1585 |
| Treatment regimen | ||||
| Neoadjuvant RT | Ref. | Ref. | ||
| Adjuvant RT | 1.10 (0.90, 1.35) | 0.3689 | 1.16 (0.96, 1.40) | 0.1273 |
| Surgery + Chemotherapy-Only | 1.12 (0.93, 1.35) | 0.2382 | 1.18 (0.99, 1.41) | 0.0653 |
HR Hazard Ratio