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. Author manuscript; available in PMC: 2019 Oct 8.
Published in final edited form as: Curr Biol. 2018 Sep 20;28(19):3086–3097.e4. doi: 10.1016/j.cub.2018.08.001

Figure 4. Mutating conserved cysteines in UNC-84 or ANC-1 disrupts nuclear anchorage.

Figure 4.

(A-F) Lateral views of L4 or young adult animals expressing GFP in hypodermal nuclei in the following genotypes: (A) wild type; (B) anc-1(e1873); (C) unc-84(n369); (D) anc-1(CC-23–24AA); (E) unc-84::gfp; (F) unc-84(C953A), and (G) anc-1(F-7A). (H) Quantification of nuclear anchorage defects assayed by counting average number of hypodermal nuclei in clusters of two or more nuclei on one lateral side of an animal. Error bars are 95% CI; *** indicates a p-value<0.0001 in a t-test when compared to wild type; all sample sizes are ≥ 20 animals. Scale bar is 25 μm.