Table 2. .  The complete blood count analysis of H1975 xenograft bearing mice treated with paclitaxel, paclitaxel–disulfide cross-linking micelle, AZD9291, AZD9291–disulfide cross-linking micelle and the combination (n = 3).

Treatment groups	WBC (K/μl)	RBC (M/μl)	Hematocrit (%)	Hemoglobin (g/dl)	Platelets (K/μl)
PBS	7.1 ± 1.8	8.4 ± 2.4	41.9 ± 9.3	10.3 ± 2.5	995 ± 35
PTX	2.1 ± 0.8†	5.7 ± 0.7	33.1 ± 6.8	9.2 ± 1.6	793 ± 34
PTX–DCM	5.9 ± 0.2	7.8 ± 0.2	44.4 ± 3.1	12.5 ± 0.1	944 ± 36
AZD9291	5.2 ± 0.9	8.4 ± 0.5	38.9 ± 1.2	13.4 ± 0.3	875 ± 42
AZD9291–DCM	9.4 ± 1.6	8.8 ± 0.7	38.1 ± 7.1	12.2 ± 0.5	857 ± 34
PTX–DCM + AZD9291–DCM	4.8 ± 1.2	8.3 ± 0.5	35.3 ± 5.2	13.2 ± 0.3	973 ± 21

^†p < 0.05 compared with phosphate-buffered saline.

DCM: Disulfide cross-linking micelle; PTX: Paclitaxel; RBC: Red blood cell; WBC: White blood cell.