Skip to main content
. 2018 May 23;13(9):1051–1066. doi: 10.2217/nnm-2017-0328

Figure 2. . Evaluation of DNA transfection efficiency of PEGylated-poly(lactic-co-glycolic acid)/polyethyleneimine nanoparticles in MDA-MB-231 triple negative breast cancer cells.

Figure 2. 

Various concentration of PEGylated-poly(lactic-co-glycolic acid)/polyethyleneimine nanoparticles was complexed with 1 μg of pcDNA-TK-NR plasmid DNA and transfected to MDA-MB-231 cells for 24 h. The cells were evaluated for nitroreductase enzyme activity using CytoCy5S substrate; Top row: bright filed images of respective condition; Bottom row: Cy5 fluorescence images of cells at respective condition. Images were taken at 20× magnification and Cy5 fluorescence was adjusted to same intensity scale.

NP: Nanoparticles.