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. 2018 Jul 4;13(12):1417–1432. doi: 10.2217/nnm-2018-0011

Figure 8. . 1,25(OH)2D3-loaded poly(ϵ-caprolactone) nanofibers induce hCAP18/LL37 production in human skin explants.

Figure 8. 

(A) An artificial wound (epidermal and partial dermal layer 1-mm thick) with diameter of 8 mm was created in each skin explant (Ctr: without any treatment). (B) Nanofibrous dressings containing either VD-PCL or vehicle (PCL) were placed in the wound. (C) Appearance of the skin tissue and nanofiber dressing after 5 days of culture. (D) Quantification of hCAP18/LL-37 production by ELISA after treatment for 1, 3 and 5 days. *p < 0.05.

Ctr: Control; PCL: Poly(ϵ-caprolactone); VD: 1,25(OH)2D3.