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. Author manuscript; available in PMC: 2019 Oct 28.
Published in final edited form as: J Control Release. 2018 Sep 6;288:111–125. doi: 10.1016/j.jconrel.2018.09.003

Figure 9.

Figure 9.

PIP 640 selectively enhances apical to basal paracellular permeability of positively-charged dextran in vitro. A) Demonstration of reversibility of TEER values following washout 60 min after apical exposure to 1 mM PIP 640 in Caco-2 cells monolayer used to assess dextran permeability. B) Cumulative apical to basal transport after 60 min of positively-charged DEAE-dextran (+ve) or negatively-charged CM-dextran (-ve) compared to neutral dextran (all 4-kDa in size). Data are means ± SEM (*P < 0.05, **P < 0.01 and ***P <0.001).

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