Table 2.
Samples | Primary-recurrent pairs | |
---|---|---|
Total tumor samples | 100 | 50 |
Evaluable HRD scores | 88% (88/100) | 78% (39/50) |
High HRD score ( ≥ 42) | 57% (50/88) | 56% (22/39) a |
BRCA1 mutation | 26% (26/100) | 26% (13/50) |
BRCA2 mutation | 6% (6/100) | 6% (3/50) |
BRCA1 methylation | 10% (10/100) | 12% (6/50) b |
aPositive in both the primary and recurrent specimen
bPositive in the primary and/or recurrent specimen (two pairs were discordant)