Fig. 4.

Estimated dietary intake of pharmaceuticals by two representative invertebrate predators compared to recommended human pharmaceutical doses. Dietary intake rates as a percentage of recommended human pharmaceutical daily doses by therapeutic class for platypus (pink) and brown trout (blue) in Brushy Creek. (CCBs calcium channel blockers, GORD gastroesophageal reflux disease, NSAID non-steroidal anti-inflammatory drugs, RAS renin angiotensin system). Calculations appear in Methods section (equations 2–5). The trout and platypus images in this figure were adapted from Harter, Jim. ‘Animals 1419 copyright-free illustrations of mammals, birds, fish, insects, etc. A pictorial archive from Nineteenth century sources’ Mineola, New York. Copyright Dover Publication Inc. (1979). All rights reserved