Fig. 2.

Cr-catalyzed para-selective alkylation of benzamides with tert-butyl Grignard reagent. Conditions: N-methylbenzamide derivative (0.2 mmol), tert-butylmagnesium bromide (0.8 mmol), CrCl₃ (0.02 mmol), TMSBr (0.6 mmol), THF (0.5 mL), rt, 24 h. Isolated yields are given. ^aYield of gram-scale reaction with 1a (10 mmol, 1.36 g). ^bTert-butylmagnesium bromide (1 mmol) was employed