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. 2018 Nov 6;8:16451. doi: 10.1038/s41598-018-34902-w

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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FABP4 is excreted to urine in kidney-specific megalin-KO mice (NDRG1 cre ERT2, megalin flox/flox). (A) Levels of FABP4 and albumin in urine. Note that FABP4 levels were markedly elevated in urine in megalin KO mice while it was hardly detected in urine in control (megalin flox/flox). (B) Levels of FABP4 and albumin in serum. n = 5. *p < 0.05 and ***p < 0.001.