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. 2018 Nov 6;8:16451. doi: 10.1038/s41598-018-34902-w

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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QCM analysis for the binding of FABP4 to megalin. FABP4 (1 mg/ml) was injected at the time point indicated by the arrow into the QCM chamber in which megalin or FA-free BSA had been immobilized on the sensor chips. The binding of FABP4 to the chip-immobilized protein is indicated by a change in the frequency, ΔF. All the experiments were repeated at least three times and the representative result is shown. Note that FABP4 bound to megalin, but not to albumin.