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. 2018 Nov 6;8:16392. doi: 10.1038/s41598-018-34304-y

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Visualization of the transmembrane potential of one of the simulations performed during Monte Carlo analysis using the ventricular wedge containing the small scar. This is one of the observed sustained reentries with ϕ = 0.66 and [ATP_i] = 2 mM. (a) A single stimulus is applied at the right region of the wedge. (b) The AP wave propagates towards the left of the LV wedge. (c) The LV wedge is almost fully depolarized. Micro-reentries lead to the formation of a fractionated figure-of-eight pattern inside the infarct region. (d) The LV wedge begins to repolarize. (e) Two ectopic beats simultaneously leave the infarct region and re-excite the healthy tissue. (f and g) The LV wedge begins to depolarize again. Inside the infarct region a fractionated figure-of-eight pattern persists (h). Healthy tissue repolarizes. (i) The sustained fractionated figure-of-eight pattern re-excites the tissue again.