Figure 6.

Chronic ethanol consumption alters bacterial communities and subsequently critical metabolic pathways in a dose-dependent manner. Heatmaps of (A) OTU (refer to Tables S5-S8) and (B) KEGG genes (refer to Tables S9-S12) that significantly correlated with average daily BEC either in a positive or negative manner as determined by the Spearman correlation coefficient (n = 12/gut region). Correlations were defined as those with an r-value ≥0.5 or ≤−0.5, and a p-value <0.05. Single and double hyphens in the cells indicate p < 0.05 and p < 0.01, respectively.