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. 2018 Oct 19;9(82):35313–35326. doi: 10.18632/oncotarget.26238

Figure 3. Competitive bone marrow transplant with wild type (wt) and Wt1+/R394W progenitor cells.

Figure 3

(A) Competitive transplant schema. N = 5 mice in each test group (wt or Wt1+/R394W CD45.2 cells). (B) Engraftment contribution of CD45.2 bone marrow to each individual progenitor cell compartment at 16 weeks after transplant. Ratio of 1 (dotted horizontal line) defines an equal contribution of CD45.2 cells to that compartment normalized to the amount of CD45.2 cells in the total bone marrow. (ST-HSCs = short-term hematopoietic stem cells, LT-HSCs = long-term hematopoietic stem cells, CMP = common myeloid progenitors, GMP = granulocyte-monocyte progenitors, and MEP = megakaryocyte-erythroid progenitors). Error bars represent the SD.