Table 3. Associations of target SNPs between cases and controls in different ethnicities and meta-analysis results.
| GENE | SNP | Genotype (AA/AB/BB)* | OR (95%CI) | P | P-meta* | I2 | P-het | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Case (HUI) | Case (HAN) | Control (HUI) | Control (HAN) | HUI | HAN | HUI | HAN | |||||
| PCMTD1–ST18 | rs1015213 | 85/8/0 | 391/16/0 | 125/4/0 | 570/21/0 | 2.673(0.7114~10) | 0.9394(0.4454~1.981) | 0.1442 | 0.8697 | 0.5645 | 45.3 | 0.1764 |
| PLEKHA7 | rs11024102 | 28/46/19 | 128/190/89 | 41/57/31 | 216/273/102 | 0.9852(0.6641~1.462) | 1.21(0.9887~1.481) | 0.941 | 0.06439 | 0.107 | 0 | 0.3635 |
| COL11A1 | rs3753841 | 37/41/15 | 178/186/43 | 60/59/10 | 281/260/50 | 1.603(1.035~2.481) | 1.247(0.9989~1.557) | 0.0344 | 0.0512 | 0.006992 | 0.9 | 0.3151 |
| EPDR1 | rs3816415 | 74/18/1 | 315/83/9 | 108/17/4 | 461/121/9 | 1.072(0.5815~1.977) | 1.08(0.7942~1.468) | 0.8235 | 0.6242 | 0.5969 | 0 | 0.9872 |
| CHAT | rs1258267 | 63/25/5 | 238/151/18 | 72/48/9 | 302/245/44 | 0.6806(0.4178~1.109) | 0.7146(0.5631~0.9069) | 0.1223 | 0.00571 | 0.001571 | 0 | 0.8604 |
| GLIS3 | rs736893 | 57/34/2 | 227/152/28 | 58/57/14 | 289/253/49 | 0.5454(0.3357~0.886) | 0.7729(0.6144~0.9724) | 0.01437 | 0.02787 | 0.002401 | 38.28 | 0.2031 |
| FERMT2 | rs7494379 | 47/31/15 | 203/165/39 | 59/61/9 | 252/265/74 | 1.034(0.6763~1.581) | 0.7906(0.6371~0.9811) | 0.8772 | 0.03287 | 0.06688 | 18.05 | 0.2693 |
| DPM2–FAM102A | rs3739821 | 38/43/12 | 201/165/41 | 49/60/20 | 317/233/41 | 0.9224(0.6089~1.397) | 1.157(0.9243~1.449) | 0.7028 | 0.2031 | 0.3484 | 0 | 0.3467 |
MAF, minor allele frequency; OR, odds ratio; CI, confidence interval; I2: measures heterogeneity, p-het: p-value for heterogeneity; p-value and OR, CI were calculated with logistic regression model by adjusting for age and gender.
*P-meta, p-value obtained by meta-analysis, if the I2 value was ≥50%, take the value of random-effects; otherwise, a fixed-effects model was adopted.