Table 4. Association between the eight PACG susceptibility loci and AL and ACD.
GENE | SNP | Minor allele | AL (22.92 ± 0.891;20.01~25.51)* | ACD (2.74±0.474;0.25~4.51)* | ||||
---|---|---|---|---|---|---|---|---|
β | SE | P | β | SE | P | |||
PCMTD1–ST18 | rs1015213 | T | -0.020 | 0.0878 | 0.821 | -0.043 | 0.0588 | 0.464 |
PLEKHA7 | rs11024102 | C | -0.022 | 0.030 | 0.470 | -0.012 | 0.0184 | 0.510 |
COL11A1 | rs3753841 | G | -0.013 | 0.0317 | 0.692 | -0.046 | 0.0201 | 0.023 |
EPDR1 | rs3816415 | A | -0.034 | 0.0447 | 0.453 | -0.035 | 0.0256 | 0.173 |
CHAT | rs1258267 | G | 0.043 | 0.0352 | 0.225 | 0.054 | 0.0223 | 0.016 |
GLIS3 | rs736893 | A | 0.057 | 0.0335 | 0.091 | 0.058 | 0.0223 | 0.010 |
FERMT2 | rs7494379 | T | 0.007 | 0.0313 | 0.830 | 0.033 | 0.0191 | 0.088 |
DPM2–FAM102A | rs3739821 | G | -0.018 | 0.0336 | 0.603 | -0.009 | 0.0205 | 0.678 |
* Numbers in parentheses indicate the mean ± SD and the range of measured values for AL or ACD
β, per-allele effect in ACD/AL; SE, standard error for ascertainment of β; P, p-value for association adjusted for age and gender.