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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Demography. 2018 Oct;55(5):1855–1885. doi: 10.1007/s13524-018-0707-2

Table 5.

Percentage of excess mortality attributable to smoking, U.S. adults ages 35+ years

Female
Male
Causes of Death Death Rates
Among
Current
Smokers
Death Rates
Among
Never
Smokers

% of Excess
Death due to
Each Cause
Death Rates
Among
Current
Smokers
Death Rates
Among
Never
Smokers

% of Excess
Death due to
Each Cause
Diseases Established as Caused by Smoking 80.8 80.3
  Lip and oral cavity cancer 5.9 1.7 0.5 24.2 1.1 1.7
  Esophageal cancer 4.5 1.5 0.4 29.7 8.7 1.5
  Stomach cancer 5.1 2.5 0.3 8.1 7.2 0.1
  Colorectal cancer 33.6 23.9 1.2 42.8 30.8 0.9
  Liver cancer 7.5 2.4 0.6 19.1 6.8 0.9
  Pancreatic cancer 26.6 16.4 1.2 58.2 24.3 2.4
  Laryngeal cancer 3.9 0.2 0.4 7.1 2.2 0.4
  Lung cancer 255.0 15.6 28.8 377.3 43.1 24.0
  Cervical cancer 3.4 0.1 0.4
  Urinary bladder cancer 8.8 2.0 0.8 49.7 8.0 3.0
  Kidney and renal pelvis cancer 3.6 1.2 0.3 11.3 5.2 0.4
  Acute myeloid leukemia 5.9 2.3 0.4 16.1 4.5 0.8
  Diabetes 17.9 15.7 0.3 35.0 15.8 1.4
  Ischemic heart disease 190.1 101.1 10.7 424.4 249.9 12.5
  Other heart disease 75.7 58.7 2.0 99.6 67.1 2.3
  Stroke 97.5 81.8 1.9 159.4 74.9 6.1
  Atherosclerosis 5.3 2.3 0.4 7.1 5.0 0.2
  Aortic aneurysm 10.2 3.3 0.8 31.8 5.0 1.9
  Other arterial diseases 8.2 1.4 0.8 10.1 3.5 0.5
  Pneumonia, influenza, and tuberculosis 43.2 21.2 2.6 91.3 34.9 4.0
  Chronic obstructive pulmonary disease 227.2 12.3 25.8 246.4 30.5 15.5
Additional Diseases Associated With Smoking 14.8 14.4
  All other infections 20.8 12.3 1.0 35.7 15.8 1.4
  Breast cancer 44.4 39.5 0.6
  Prostate cancer 54.0 44.2 0.7
  Rare cancers 36.8 23.1 1.6 40.9 17.8 1.7
  Cancers of unknown site 21.2 6.2 1.8 40.2 9.4 2.2
  Hypertensive heart disease 13.7 12.7 0.1 23.6 6.6 1.2
  Essential hypertension/hypertensive renal disease 15.5 5.4 1.2 6.1 2.3 0.3
  All other respiratory diseases 08.0 6.6 0.2 24.9 23.3 0.1
  Intestinal ischemia 18.9 3.7 1.8 19.8 3.4 1.2
  Liver cirrhosis 12.6 4.9 0.9 27.4 7.6 1.4
  All other digestive diseases 31.3 16.2 1.8 57.3 15.1 3.0
  Renal failure 5.2 4.9 0.0 20.3 20.4 0.0
  Additional rare causes combined 33.1 15.3 2.1 18.5 11.8 0.5
  Unknown causes 15.1 2.6 1.5 15.0 5.5 0.7
Causes not Linked to Smoking 256.7 219.9 4.4 417.6 344.0 5.3
Total Deaths 1,572.2 740.5 2,550.0 1,155.7

Notes: Rates and percentages are age-adjusted using the 2010 U.S. population (Howden and Meyer 2011). Death rates are expressed per 100,000. Models adjust for age, race/ethnicity, educational attainment, marital status, region, BMI, and health insurance status. Diseases established as caused by smoking are those recognized by the surgeon general (U.S. DHHS 2014). Additional diseases associated with smoking are those compiled by Carter et al. (2015). Dashes indicate sex-specific causes of death (e.g., cervical and breast cancer among women and prostate cancer among men).

Source: 1990–2011 NHIS-LMF