Figure 3.
Crat in AgRP neurons affects hepatic function in response to CR. A, B) Liver glycogen (A) and triglyceride (B) after 9 d of CR. C) Hepatic gene expression of enzymes involved in gluconeogenesis, glycogenolysis, lipogenesis, and lipolysis. D–K) Plasma profiles after CR of metabolites: NEFA (D), triglycerides (E), and ketone bodies (F), and hormones: corticosterone (G), insulin (H), glucagon (I), acyl-ghrelin (J), and leptin (K). All data are expressed as means ± sem; n = 6–9. P < 0.05 (2-tailed, unpaired Student’s t test).
