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The expression of the Tgr5 gene as well as TGR-5–regulated signaling genes. A–C) Gene expression in the liver (A), adipose tissue (B), and ileum(C). D) Serum PYY level after 12 h of food withdrawal. E) GLP-1 secretion after liquid diet stimulation. The AUC is shown (n = 3–4/group). Data are means ± sd. *P < 0.05, **P < 0.01, ***P < 0.001 (1-way ANOVA with Tukey’s correction).
