Table 1. Comparison of mean OD values for antibodies and blood cell counts between Helicobacter pylori-infected and noninfected mice.
| Strains of mice | Number ofmice tested | HPinoculation | PCR for detection of HP Number of positive samples | ELISA antibody against HPMean of OD490 value ± SD | P value* | Platelet count (×104 cells/µl)Mean ± SD | P value* | Red blood cells (×104 cells/µl)Mean ± SD | P value* |
|---|---|---|---|---|---|---|---|---|---|
| BALB/c | 9 | + | 8 | 0.57 ± 0.28 | 0.00 | 102.28 ± 14.71 | 0.01 | 1,068.22 ± 143.43 | 0.67 |
| 10 | − | ND** | 0.12 ± 0.02 | 121.80 ± 13.30 | 1,092.90 ± 95.40 | ||||
| C57BL/6 | 10 | + | 10 | 0.60 ± 0.47 | 0.01 | 99.65 ± 17.00 | 0.56 | 957.90 ± 67.34 | 0.41 |
| 10 | − | ND** | 0.12 ± 0.02 | 104.35 ± 18.20 | 989.60 ± 97.28 | ||||
| DBA/2 | 7 | + | 6 | 0.83 ± 1.01 | 0.05 | 111.57 ± 16.20 | 0.62 | 1,110.71 ± 108.30 | 0.05 |
| 10 | − | ND** | 0.13 ± 0.04 | 107.84 ± 14.33 | 1,003.20 ± 43.12 |
*Results were compared with samples from HP infected and noninfected mice. **ND: Not done. ELISA, enzyme-linked immunosorbent assay; HP, Helicobacter pylori; OD490, optical density at 490 nm; PCR, polymerase chain reaction; SD, standard deviation.