Table 3c:
Risks of developing t-MN after autotransplant for NHL (n=3540)
Parameter | n | Hazard Ratio (95% CI) | P-value |
---|---|---|---|
Age at transplant, years | <.01 | ||
18-44 | 748 | 1.00 | |
45-54 | 938 | 2.77(1.55 - 4.93) | <.01 |
55+ | 1854 | 4.52(2.63 - 7.77) | <.01 |
No. of prior lines of chemotherapy | <.01 | ||
1 | 846 | 1.00 | |
2 | 1422 | 0.98(0.67 - 1.44) | 0.91 |
3+ | 1128 | 1.93(1.34 - 2.78) | <.01 |
Missing | 144 | 0.55(0.20 - 1.53) | 0.25 |
Conditioning | 0.04 | ||
BEAM or similar | 2316 | 1.00 | |
TBI based | 510 | 1.69(1.14 - 2.49) | 0.008 |
CBV or similar | 381 | 0.96(0.59 - 1.54) | 0.86 |
Bu+Mel/Bu+Cy | 197 | 1.75(1.03 - 2.96) | 0.04 |
Others | 136 | 1.30(0.60 - 2.82) | 0.51 |
Year of transplant | <.01 | ||
1995-1999 | 1350 | 1.00 | |
2000-2004 | 735 | 1.36 (0.91 - 2.05) | 0.14 |
2005-2010 | 1455 | 2.12 (1.47 - 3.08) | <.01 |