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. Author manuscript; available in PMC: 2019 Nov 15.
Published in final edited form as: J Immunol. 2018 Oct 5;201(10):2910–2922. doi: 10.4049/jimmunol.1700638

Figure 6. Helminth-induced suppression of GVHD and promotion of survival are dependent on host cell IL4 production. (Upper panel).

Figure 6.

Kaplan-Meier survival curves of Hpb-infected or uninfected IL4−/− male BMT recipients that received T cell-depleted (TCD-BM) cells (TCD BM) or TCD-BM plus total splenic T cells (TCD-BM + T) from 5–6 week old male WT C57BL/6 donor mice. Cumulative data from three independent experiments. N: cumulative number of BMT mice in each group; N = 10: uninfected TCD-BM; N = 10: Hpb-infected TCD-BM; N = 15: uninfected TCD-BM + T; N = 15: Hpb-infected TCD-BM + T. (Middle panel) GVHD disease score and (Lower panel) weight change of the same group of mice. Weight loss for each group of mice is displayed as percent weight change at different time points compared to initial weight.