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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Dis Colon Rectum. 2018 Dec;61(12):1350–1356. doi: 10.1097/DCR.0000000000001219

Table 2.

Patients with AIN III who were diagnosed with other primary neoplasms.

Type of other primary neoplasm Before first AIN III
diagnosis
N (%)
After first
AIN III diagnosis
N (%)

Any other primary neoplasm 935 (45.1%) 912 (44.0%)

Any other HPV-related tumor 343 (16.5%) 323 (15.6%)
  Anal carcinoma n/a 171 (8.2%)
  Cervical neoplasm 55 (2.7%) 2 (0.1%)
  Oropharyngeal malignancy 15 (0.7%) 22 (1.1%)
  Penile malignancy 5 (0.2%) 6 (0.3%)
  Vaginal malignancy 27 (1.3%) 10 (0.5%)
  Vulvar malignancy 278 (13.4%) 117 (5.6%)

Any AIDS-defining malignancy 262 (12.6%) 56 (2.7%)
  Kaposi sarcoma 172 (8.3%) 24 (1.2%)
  Non-Hodgkin lymphoma 89 (4.3%) 30 (1.4%)
  Cervical cancer 8 (0.4%) 2 (0.1%)

AIN: anal intraepithelial neoplasia; HPV: human papillomavirus; AIDS: acquired immune deficiency syndrome