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. 2018 Oct;9(5):962–971. doi: 10.21037/jgo.2017.11.07

Table 1. Published prospective trials evaluating proton beam radiotherapy for hepatocellular carcinoma.

Study (year published) No. patients Child-Pugh class A (%) Dose/fractions Local control, 3 years (%) Survival, 3 years (%)
Kawashima [2005] 30 66 76 Gy/20 fx 96 62
Fukumitsu [2009] 51 80 66 Gy/10 fx 95 49
Bush [2011] 76 29 63 Gy/15 fx 80* ~24
Hong [2016] 44 73 58 Gy/15 fx 95 (2 years) 63 (2 years)
Bush [2016] 33 N.R. 70.2 Gy/15 fx 88 N.R.

*, crude rate. N.R., not reported.