Table 1.

CONRAD 135 study design

Product	Visit 1	Visit 2	Visit 3	Visit 4	Visit 5
Intravaginal ring (IVR) (n = 20)	Screening	Insert IVR1 (24–36 h)	Remove IVR1 Vaginal swab Insert IVR2 (7–10 days)	Remove IVR2 Vaginal swab Insert IVR3 (28–32 days)	Remove IVR3 Vaginal swab
Gel, film, or insert (n = 10 each)	Screening	Baseline swab Apply product in clinic Swab 15 min post-product Swabs at home each day, Day 1–Day 7	Baseline swab Apply product in clinic Swabs 15 min post-product Unprotected intercourse 8–16 h post-product use Swabs at home each day, Day 1–Day 7	Final swab	N/A