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. 2018 Aug 23;26(11):521–532. doi: 10.1007/s12471-018-1148-7

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 3 — a–c Cardiac magnetic resonance imaging. Cardiac magnetic resonance imaging with T1 mapping in a female breast cancer survivor, treated with anthracyclines. Extracellular volume fraction (ECV) is a non-invasive measurement of diffuse myocardial fibrosis and can be calculated from the haematocrit; pre-contrast (a), post-contrast (b) T1 maps. In this patient, the ECV map (c) reveals diffuse elevated ECV values up to 42% (normal is <28%), in particular in the septal segments, reflecting widespread myocardial fibrosis after anthracycline exposure