Fig. 4.

a–c Response and outcome to heart failure (HF) treatment in patients with chemotherapy-related cardiac dysfunction. a Percentage of (partial) responders according to the time elapsed from diagnosing left ventricular dysfunction and start of HF therapy. b Left ventricular ejection fraction in patients with cardiotoxicity and with no (square/red), partial (triangle/blue) or full (dot/green) recovery following heart failure therapy. c Cumulative cardiac event rate during follow-up. Reprinted from: [3, 49]. CT Chemotherapy