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. 2018 Oct 31;9:1237. doi: 10.3389/fphar.2018.01237

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Copyright © 2018 Qiu, Guo, Liu, Luo, Fan, Deng, Cui, Lu, Zhang, He and Lu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PZH inhibited the activities of Th1 and Th17 cell subsets. Mice were sacrificed at day 70 p.i., and the brain tissue were collected. The mRNA levels of T-bet (A), IFN-γ (B), ROR-γt (C), and IL-17A (D) were analyzed by real-time PCR. All data were expressed as mean ± SD (n = 5 each group; ^*P < 0.05; ^**P < 0.01).