Table 3.
Effects of verapamil on NAFLD activity score (NAS).
| Item | ND | ND+VER | HFD | HFD+VER |
|---|---|---|---|---|
| Steatosis | 0.00 ± 0.00 | 0.00 ± 0.00 | 2.96 ± 0.52** | 1.56 ± 0.53# |
| Lobular inflammation | 0.00 ± 0.00 | 0.00 ± 0.00 | 1.36 ± 0.29** | 0.78 ± 0.32# |
| Hepatocellular ballooning | 0.00 ± 0.00 | 0.00 ± 0.00 | 1.41 ± 0.53** | 0.35 ± 0.11## |
| NAS | 0.00 ± 0.00 | 0.00 ± 0.00 | 5.65 ± 0.53 | 3.36 ± 0.53# |
Data are expressed as mean ± SD (n = 10 per group).
**
p < 0.01 vs. ND group.
#
p < 0.05,
##
p < 0.01 vs. HFD group.
ND, normal diet; VER, verapamil; HFD, high-fat diet; NAS, NAFLD activity score.