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. 2018 Oct 31;9:1451. doi: 10.3389/fphys.2018.01451

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Copyright © 2018 Matos, Vieira, Pinhal, Lopes, Dias-Peixoto, Pauli, Magalhães, Little, Rocha-Vieira and Amorim.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representative blot and data of the phosphorylation of IRS (Tyr 612), Akt (Ser 473), AS160 (Thr 642) and expression of GLUT4 in skeletal muscle of CON, OB, and OBR at baseline (A–D) and in OB and OBR groups before and after HIIT (OBT and OBRT) (E–H). Data are expressed as mean ± standard deviation, considering the control as 100%. CON: non-obese and non-insulin resistant; OB: obese non-insulin resistant pre-training; OBT: obese post-training non-insulin resistant; OBR: obese insulin resistant pre-training and OBRT: obese insulin resistant post-training. ^∗Indicates difference between OB and CON at baseline (p < 0.05). ^∗∗Indicates difference between OBR and CON at baseline (p < 0.05). ^#Indicates training effect (p < 0.05). CON (n = 3–5), OB (n = 7–8), and OBR (n = 6–7).