Table 4.
Multivariate analysis of risk factors affecting neck metastasis
| Step | Variable | OR | 95% CI | P value |
|---|---|---|---|---|
| Step 1 | ||||
| T classification | 31.95 | 2.410-423.574 | 0.009* | |
| Lymphatic invasion | 24.52 | 1.004-598.535 | 0.050* | |
| Flt-4 | 68.05 | 0.775-5976.283 | 0.065 | |
| VEGF-C | 7.77 | 0.45-133.979 | 0.158 | |
| CNTN-1 | 1.36 | 0.031-59.483 | 0.874 | |
| Step 2 | ||||
| T classification | 31.43 | 2.474-399.297 | 0.008* | |
| Lymphatic invasion | 25.43 | 1.081-598.532 | 0.045* | |
| Flt-4 | 64.59 | 0.838-4980.629 | 0.060 | |
| VEGF-C | 8.29 | 0.528-130.214 | 0.132 | |
| Step 3 | ||||
| T classification | 25.74 | 3.112-212.947 | 0.003* | |
| Lymphatic invasion | 27.14 | 1.543-477.394 | 0.024* | |
| Flt-4 | 48.14 | 1.078-2150.297 | 0.046* |
OR, odds ratio; CI, confidence interval.
*
Statistically significant according to multiple logistic regression analysis.