Table 1.

Potential role of m⁶A regulators in different cancers

Cancer	m6A regulators	Related genes	Potential Role	Ref.
AML	METTLE3	C-MYC and BCL2	Oncogene	[28]
	METTLE14	MYB, MYC	Oncogene	[29]
	WTAP	N	Oncogene	[33]
Cervical cancer	METTL3/METTL14	N	Tumor-suppressor	[30]
	FTO/ALKBH5	N	Oncogene	[30]
Breast cancer	ALKBH5	NANOG	Oncogene	[39]
Colorectal cancer	YTHDF1	Associated with c-Myc	Oncogene	[52]
Glioblastoma	METTL3/METTL14	ADAM19	Tumor-suppressor	[27]
	ALKBH5	FOXM1	Oncogene	[38]
HCC	METTLE14	miR126	Tumor-suppressor	[34]
	YTHDF2	Associated with miR-145	Oncogene	[53]
Lung cancer	METTLE3	EGFR, TAZ, DNMT3A	Oncogene	[25]
MLL-rearranged AML	FTO	ASB2, RARA	Oncogene	[36,37]
Renal cell carcinoma	METTL3	PI3K-Akt-mTOR pathways	Tumor-suppressor	[31]
	WTAP	Associated with CDK2	Oncogene	[34]

Note: N means there are no known relevant genes in this review.