Table 1.
Treatment plan for the ACS c-SLNs in vivo chemoprevention study in the LSL-KrasG12D/+; Pdx-1Cre/+ PDAC mouse model
| Group (G) (3 Male + 3 Females/Group) | Treatment Plan (Oral Gavage) | Dose mg/kg (ASP + CUR + SFN) | |
|---|---|---|---|
| G1 | Saline control | Saline | 0 |
| G2 | c-SLN vehicle control | Blank c-SLNs (drug free) | 0 |
| G3 | Low dose of ACS cSLNs | ASP c-SLNs + CUR c-SLNs + SFN | 2 + 4.5 + 0.16 |
| G4 | Medium dose of ACS cSLNs | ASP c-SLNs + CUR c-SLNs + SFN | 20 + 45 + 1.6 |
| G5 | High dose of ACS cSLNs | ASP c-SLNs + CUR c-SLNs + SFN | 60 + 135 + 4.8 |