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HO virulence genes evolve at an accelerated rate
| Mtb virulence genes | ||
|---|---|---|
| Avg. dN/dS | % dN/dS > 1 | |
| CD | 0.77 ± 0.20 | 33% |
| HO | 1.52 ± 0.27 | 58% |
Mutation rates of virulence genes were analyzed by gene orientation (15 co-directional and 12 head-on core genes). Student’s t test p = 0.035 for HO vs. CD average dN/dS values
