Skip to main content
. 2018 Nov 7;8:16506. doi: 10.1038/s41598-018-34873-y

Figure 7.

Figure 7

Th1 cytokine production by unconventional T cells. Gating strategy for post stimulation identification of TNF and IFNγ producing MAIT cells (a), γδ T cells (b) and type I NKT cells (c) from the peripheral blood from healthy donors (HD) and patients with LCH (PB), and from lesional T cells from patients with active LCH. (d) Proportions of TNF+ and/or IFNγ+ T cells in MAIT cells, γδ T cells and type I NKT cells from the peripheral blood from healthy donors (HD), patients with non-active LCH (PB-NAD) and active LCH (PB-AD) and in lesional T cells from patients with active LCH. Kruskal-Wallis tests with Dunn’s multiple comparisons were conducted for (d) (groups with only one value excluded), except where only two groups were compared (Mann Whitney test), error bars indicate median + interquartile range, 10−3 on logarithmic scale indicates ‘undetectable’.