. 2018 Oct 15;10(10):3276–3290.

Table 2.

The rat body weights and levels of proteinuria, serum UA, BUN, and creatinine before and after treatment with GTPs

	Group	4 w	8 w	12 w
Body weight	Sham	50.00 ± 10.00	73.57 ± 20.14	101.67 ± 18.92
	RK	35.71 ± 6.34^a	49.28 ± 8.38^a	71.00 ± 11.40^a
	RK + OA	24.00 ± 6.48^a,^b	25.71 ± 7.86^a,^b	48.57 ± 16.51^a,^b
	RK + OA + Tea low dose	25.00 ± 5.77^a,^b,^c	41.00 ± 7.07^a,^c	66.00 ± 5.70^a,^c
	RK + OA + Tea high dose	28.00 ± 6.89^a,^b,^c	52.87 ± 9.35^a,^c	69.34 ± 3.67^a,^c
	RK + OA + AP	16.25 ± 6.29^a,^b,^c	39.33 ± 8.75^a,^c	65.00 ± 10.36^a,^c
Proteinuria	Sham	3.12 ± 1.06	3.10 ± 1.00	3.16 ± 0.95
	RK	5.31 ± 1.72^a	7.13 ± 1.21^a	7.64 ± 1.61^a
	RK + OA	8.40 ± 2.05^a,^b	9.49 ± 1.55^a,^b	5.58 ± 1.29^a,^b
	RK + OA + Tea low dose	5.42 ± 1.49^a,^c,^d	4.26 ± 1.04^b,^c	5.13 ± 1.44^a,^b
	RK + OA + Tea high dose	5.25 ± 1.34^a,^c,^d	4.15 ± 0.87^b,^c	4.64 ± 1.05^a,^b
	RK + OA + AP	7.77 ± 2.26^a,^b	5.72 ± 1.57^a,^c	5.59 ± 1.79^a
Serum UA	Sham	87.10 ± 23.06	87.60 ± 21.30	86.93 ± 20.63
	RK	87.88 ± 28.49	102.55 ± 22.52	77.66 ± 20.75
	RK + OA	206.10 ± 59.15^a,^b	226.48 ± 36.89^a,^b	195.88 ± 51.67^a,^b
	RK + OA + Tea low dose	180.82 ± 38.04^a,^b	153.96 ± 31.52^a,^b,^c	143.38 ± 36.68^a,^b,^c
	RK + OA + Tea high dose	175.35 ± 34.16^a,^b	137.58 ± 28.18^a,^b,^c	130.74 ± 40.34^a,^b,^c
	RK + OA + AP	154.24 ± 28.55^a,^b,^c	147.95 ± 25.27^a,^b,^c	135.05 ± 33.80^a,^b,^c
BUN	Sham	5.34 ± 1.40	5.31 ± 1.32	5.27 ± 1.46
	RK	8.77 ± 1.25^a	10.74 ± 1.08^a	12.13 ± 1.48^a
	RK + OA	11.66 ± 0.91^a,^b	13.06 ± 2.72^a,^b	15.72 ± 4.43^a,^b
	RK + OA + Tea	12.64 ± 2.23^a,^b	9.44 ± 1.38^a,^c,^d	9.54 ± 1.53^a,^c
	RK + OA + AP	12.28 ± 3.77^a,^b	13.37 ± 1.58^a,^b	11.18 ± 2.15^a,^c
Creatinine	Sham	52.36 ± 11.75	52.36 ± 10.77	57.85 ± 9.81
	RK	68.03 ± 12.56^a	70.05 ± 9.07^a	78.20 ± 13.73^a
	RK + OA	88.10 ± 15.15^a,^b	93.15 ± 16.42^a,^b	102.30 ± 20.15^a,^b
	RK + OA + Tea	87.32 ± 10.74^a,^b	73.25 ± 10.93^a,^c	66.13 ± 9.62^c,^d
	RK + OA + AP	97.64 ± 7.33^a,^b	75.33 ± 12.81^a,^c	83.48 ± 10.59^a,^c

P < 0.05 vs. Sham;

P < 0.05 vs. RK;

P < 0.05 vs. RK + OA;

P < 0.05 vs. RK + OA + AP.

AP: allopurinol.